Increased Matrix Metalloproteinase 9 Activity in Mild Cognitive Impairment
نویسندگان
چکیده
منابع مشابه
Increased matrix metalloproteinase 9 activity in mild cognitive impairment.
Nerve growth factor (NGF)-dependent cholinergic basal forebrain neurons degenerate during the progression of Alzheimer disease (AD). Elevated proNGF and reduced levels of the TrkA high-affinity NGF receptor occur in prodromal and advanced stages of AD. We recently described a protease cascade responsible for the conversion of proNGF to mature NGF (mNGF) in which matrix metalloproteinase 9 (MMP-...
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Background: Meningioma is one of the most common tumors of the central nervous system. It was shown that meningioma had up-regulated expression of Matrix Metalloproteinases (MMPs) that involved in cell growth, angiogenesis and metastasis. Objectives: The aim of the study was the assessment of serum MMP-2 and -9 levels in patients with different grades of meningioma. Materials & Me...
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Objective Matrix Metalloproteinase (MMPs) play important roles in the structural and functional properties of reproductive organs. The aim of this study is to determine the prevalence of C-1562T Matrix Metalloproteinase-9 (rs3918242) gene polymorphism in fertile and infertile men. In addition, we aimed to determine the association between C-1562T MMP-9 and G-1575A MMP-2 gene polymorphisms. Mate...
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BACKGROUND The impact of serum matrix metalloproteinases-9 (MMP-9) on cognitive impairment after ischemic stroke is unclear. We aimed to investigate the association between serum MMP-9 in the short-term acute phase of ischemic stroke and cognitive impairment at 3 months. METHODS AND RESULTS Our study was based on a subsample from the CATIS (China Antihypertensive Trial in Acute Ischemic Strok...
متن کاملIncreased matrix metalloproteinase-9 activity in unstable carotid plaques. A potential role in acute plaque disruption.
BACKGROUND AND PURPOSE Acute disruption of atherosclerotic plaques precedes the onset of clinical syndromes, and studies have implicated a role for matrix metalloproteinases (MMPs) in this process. The aim of this study was to establish the character, level, and expression of MMPs in carotid plaques and to correlate this with clinical status, cerebral embolization, and histology. METHODS Plaq...
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ژورنال
عنوان ژورنال: Journal of Neuropathology & Experimental Neurology
سال: 2009
ISSN: 0022-3069,1554-6578
DOI: 10.1097/nen.0b013e3181c22569